67.5 B-
Tirzepatide
Also known as: Mounjaro, Zepbound
FDA Approved Research Chemical
Research Evidence 90.0/100
Safety Profile 45.0/100
112 Clinical Trials
Unknown: 17 PHASE4: 19 PHASE3: 14 PHASE2, PHASE3: 2 PHASE2: 27 PHASE1, PHASE2: 3 PHASE1: 12 NA: 15 EARLY_PHASE1: 3
- SHAPE-ENDO: Multimodal Pre-Surgical Optimization in Patients With Obesity and Early-Stage Endometrial Cancer Unknown Phase NOT_YET_RECRUITING Hospital Universitari de Bellvitge
- Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity Unknown Phase NOT_YET_RECRUITING Radboud University Medical Center
- Safety and Effectiveness of Tirzepatide in Patients With Obesity at Hospital de Clínicas, Paraguay Unknown Phase NOT_YET_RECRUITING LABORATORIOS INDUFAR
- GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound Unknown Phase RECRUITING Medical University of South Carolina
- Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock Unknown Phase NOT_YET_RECRUITING National University of Singapore
Showing 5 of 112 trials.
20 Research Papers
- Tirzepatide in Metabolic Diseases: Clinical Efficacy and Safety Beyond Diabetes and Obesity. Med Res Rev Review
- Childhood Obesity and Cardiac Risk in Youth: Emerging Challenges Toward 2050. Clin Nutr ESPEN Review
- Weight Loss With GLP-1 Agonists in Nondiabetic Adults: Systematic Review and Network Meta-Analysis. Obesity (Silver Spring) Review
- Tirzepatide and metformin effects on hunger and BMI in an adolescent with hyperphagia and severe obesity due to MC4R Deficiency: a case report. Obes Facts unknown
- Early intervention with tirzepatide or semaglutide influences anti-atherosclerotic effects in ApoE knockout mice. Sci Rep unknown
Showing 5 of 20 papers by citation count.
FDA Data
Not FDA-Approved
Tirzepatide has not been evaluated by the FDA for safety or efficacy. It is not approved for human therapeutic use in the United States.
Frequently Asked Questions
Is Tirzepatide FDA approved?
No, Tirzepatide has not been approved by the FDA for human therapeutic use. It is sold as a research chemical.
How many clinical trials has Tirzepatide been studied in?
Tirzepatide has been studied in 112 registered clinical trials. CheckPeptides tracks phase, status, and sponsor data for each trial.
What is the trust score for Tirzepatide?
Tirzepatide has a CheckPeptides trust score of 67.5/100 (grade: B-). This score is based on clinical trial volume, research paper quality, FDA data, and evidence classification.
Last verified: April 8, 2026
Quick Facts
- Classification
- GLP-1/GIP dual receptor agonist
- Molecular Weight
- 4813.0 Da
- PubChem
- CID 166567236 ↗
- Regulatory Status
- N/A
Score Breakdown
Research Evidence 90.0/100
Safety Profile 45.0/100
Evidence Summary
- Clinical Trials
- 112
- Research Papers
- 20
- Trust Score
- 67.5/100
- Grade
- B-